Acetic Acid (0087)
[ a-cee'-tik as'-id ]
| Ingredients: |
Acetic Acid |
| Indications: |
Infection, ear, external |
| Pregnancy Category: |
(none)
|
| FDA Approved: |
1981- 12- 01 |
| Classes: |
Anti- infectives, otic; Otics |
| Brand Names: |
Acetasol
-
US
;
Aquaear
-
Australia
;
Earcalm
-
England
;
Vasotate
-
US
;
Vosol
-
US
;
|
| DEA schedules: |
(none)
|
| Cost of therapy: |
$3.78
(
External Ear Infections ;
Generic Otic Solution (Watson) ;
2%; 15 ml ;
20 drops/day ;
7 day supply
)
$4.31
(
External Ear Infections ;
Vasotate ;
2%; 15 ml ;
20 drops/day ;
7 day supply
)
$10.50
(
External Ear Infections ;
Acetasol ;
2%; 15 ml ;
20 drops/day ;
7 day supply
)
|
DESCRIPTION
|
| |
Vosol (acetic acid otic solution) is a solution of acetic acid (2%), in a propylene glycol vehicle containing propylene glycol
diacetate (3%), benzethonium chloride (0.02%), and sodium acetate (0.015%). The empirical formula for acetic acid is CH3 COOH, with a molecular weight of 60.05.
Acetic acid is available as a nonaqueous otic solution buffered at pH 3 for use in the external ear canal.
|
CLINICAL PHARMACOLOGY
|
| |
Acetic acid is anti- bacterial and anti- fungal; propylene glycol is hydrophilic and provides a low surface tension; benzethonium
chloride is a surface active agent that promotes contact of the solution with tissues.
|
INDICATIONS AND USAGE
|
| |
For the treatment of superficial infections of the external auditory canal caused by organisms susceptible to the action of
the antimicrobial.
|
CONTRAINDICATIONS
|
| |
Hypersensitivity to acetic acid or any of the ingredients. Perforated tympanic membrane is frequently considered a contraindication
to the use of any medication in the external ear canal.
|
WARNINGS
|
| |
Discontinue promptly it sensitization or irritation occurs.
|
PRECAUTIONS
|
| |
Transient stinging or burning may be noted occasionally when the solution is first instilled into the acutely inflamed ear.
|
ADVERSE REACTIONS
|
| |
Stinging or burning may be noted occasionally; local irritation has occurred very rarely.
|
DOSAGE AND ADMINISTRATION
|
| |
Carefully remove all cerumen and debris to allow acetic acid to contact infected surfaces directly. To promote continuous
contact, insert a wick saturated with acetic acid into the ear canal; the wick may also be saturated after insertion. Instruct
the patient to keep the wick in for at least 24 hours and to keep it most by adding 3- 5 drops of acetic acid every 4- 6 hours.
The wick may be removed after 24 hours but the patient should continue to instill 5 drops of acetic acid 3 or 4 times daily
thereafter, for as long as indicated.
Storage: Store at room temperature; avoid excessive heat. Keep container tightly closed.
|
PRODUCT IDENTIFICATION
|
| |
None Available |
PRODUCT LISTING - RATED THERAPEUTICALLY EQUIVALENT
|
| |
| solution - irrigation - 0.25% -
|
| 250.0 ml x 24.0 |
$131.04 |
GENERIC
Abbott Pharmaceutical
|
00074614322 |
| 250.0 ml x 12.0 |
$233.42 |
GENERIC
Abbott Pharmaceutical
|
00074614302 |
| 500.0 ml x 6.0 |
$144.00 |
GENERIC
B. Braun/ McGaw Inc
|
00264230410 |
| 1000.0 ml x 12.0 |
$31.60 |
GENERIC
Baxter I.V. Systems Division
|
00338065604 |
| 1000.0 ml x 12.0 |
$37.04 |
GENERIC
Abbott Pharmaceutical
|
00074614309 |
| 1000.0 ml x 6.0 |
$146.40 |
GENERIC
B. Braun/ McGaw Inc
|
00264230400 |
| solution - otic - 2% -
|
| 15.0 ml |
$1.73 |
GENERIC
Morton Grove Pharmaceuticals Inc
|
60432074115 |
| 15.0 ml |
$3.32 |
GENERIC
Qualitest Pharmaceuticals Inc
|
00603703541 |
| 15.0 ml |
$3.78 |
GENERIC
Watson Pharmaceuticals
|
00364073272 |
| 15.0 ml |
$4.19 |
GENERIC
Sandoz Inc
|
00781631085 |
| 15.0 ml |
$4.25 |
Acetasol
IVAX Corporation
|
00182177564 |
| 15.0 ml |
$4.31 |
Vasotate
Major Pharmaceuticals Inc
|
00904031535 |
| 15.0 ml |
$9.98 |
GENERIC
Thames Pharmaceuticals Inc
|
49158019542 |
| 15.0 ml |
$10.50 |
Acetasol
Alpharma USPD
|
00472088099 |
| 15.0 ml |
$10.63 |
GENERIC
Allscripts Healthcare Solutions
|
54569231100 |
| 15.0 ml |
$31.00 |
GENERIC
Southwood Pharmaceuticals Inc
|
58016608201 |
| 15.0 ml x 3.0 |
$198.66 |
Vosol
MedPointe Healthcare Inc
|
00037361110 |
| 60.0 ml |
$9.00 |
GENERIC
Allscripts Healthcare Solutions
|
54569123700 |
|
PRODUCT LISTING - EQUIVALENTS NOT AVAILABLE
|
| |
| solution - compounding - 36% -
|
| 500.0 ml |
$12.38 |
GENERIC
Mallinckrodt Medical Inc
|
00019250414 |
| 500.0 ml |
$14.00 |
GENERIC
Amend Drug And Chemical Company Inc
|
17317021101 |
| 500.0 ml |
$14.68 |
GENERIC
Mallinckrodt Medical Inc
|
00406250403 |
| 500.0 ml |
$15.60 |
GENERIC
A- A Spectrum Healthcare Products
|
49452003001 |
| 2500.0 ml |
$30.80 |
GENERIC
A- A Spectrum Healthcare Products
|
49452003002 |
| 4000.0 ml |
$42.70 |
GENERIC
A- A Spectrum Healthcare Products
|
49452003003 |
| solution - otic - 2% -
|
| 15.0 ml |
$6.08 |
GENERIC
Prescript Pharmaceuticals
|
00247014215 |
|
|