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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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B
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INDICATIONS:
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Bronchitis, chronic, acute exacerbation |
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Gonorrhea |
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Impetigo |
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Infection, bone |
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Infection, central nervous system |
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Infection, ear, middle |
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Infection, joint |
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Infection, lower respiratory tract |
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Infection, sexually transmitted |
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Infection, sinus |
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Infection, skin and skin structure |
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Infection, upper respiratory tract |
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Infection, urinary tract |
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Lyme disease |
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Meningitis |
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Pharyngitis |
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Pneumonia |
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Prophylaxis, surgical |
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Septicemia |
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Tonsillitis |
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SIDE EFFECTS:
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acute generalized exanthematous pustulosis (AGEP) |
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agranulocytosis |
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anaphylactoid reactions |
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angioedema |
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aplastic anemia |
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cholestasis |
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diarrhea |
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dizziness |
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elevated hepatic enzymes |
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erythema multiforme |
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erythema nodosum |
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exfoliative dermatitis |
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headache |
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hemolytic anemia |
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hepatitis |
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jaundice |
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leukopenia |
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maculopapular rash |
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malaise |
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nausea/vomiting |
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neutropenia |
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pancytopenia |
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pruritus |
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pseudomembranous colitis |
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seizures |
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serum sickness |
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Stevens-Johnson syndrome |
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thrombocytopenia |
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toxic epidermal necrolysis |
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urticaria |
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vaginitis |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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breast-feeding |
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coagulopathy |
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colitis |
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GI disease |
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intramuscular injections |
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penicillin hypersensitivity |
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pregnancy |
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renal disease |
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renal impairment |
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ADULT DOSE:
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Bone and joint infections-Intramuscular or intravenous, 1.5 grams (base) every eight hours .
Gonococcal infections, disseminated or
Pneumonia, uncomplicated or
Skin and soft tissue infections or
Urinary tract infections, uncomplicated-Intramuscular or intravenous, 750 mg (base) every eight hours .
Gonorrhea, uncomplicated-Intramuscular, 1.5 grams (base) as a single dose at two different sites, in combination with 1 gram of oral probenecid .
Meningitis, bacterial-Intravenous, up to 3 grams (base) every eight hours .
Perioperative prophylaxis-Open heart surgery patients: Intravenous, 1.5 grams (base) at the induction of anesthesia, then 1.5 grams every twelve hours, for a total of 6 grams .
Other surgery patients: Intravenous, 1.5 grams (base) one-half to one hour prior to the start of surgery, then 750 mg (intramuscularly or intravenously) every eight hours thereafter .
For all other infections-Severe or complicated: Intramuscular or intravenous, 1.5 grams (base) every eight hours .
Life-threatening: Intramuscular or intravenous, 1.5 grams (base) every six hours .
Note: Adults with renal function impairment may require a reduction in dose .
See Cefuroxime Sodium Injection USP . |
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MAXIMUM ADULT DOSE:
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PEDIATRIC DOSE:
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Bone and joint infections-Intramuscular or intravenous, 50 mg (base) per kg of body weight, up to 1.5 grams, every eight hours .
Meningitis, bacterial-Infants and children 1 month of age and older: Intravenous, 50 to 80 mg (base) per kg of body weight every six to eight hours .
Neonates up to 4 weeks of age: Intravenous, 33.3 to 50 mg (base) per kg of body weight every eight to twelve hours .
For all other infections-Infants and children 1 month of age and older: Intramuscular or intravenous, 12.5 to 33.3 mg (base) per kg of body weight every six to eight hours .
Neonates up to 4 weeks of age: Intravenous, 10 to 50 mg (base) per kg of body weight every eight to twelve hours .
Note: Pediatric patients with renal function impairment may require a reduction in the frequency of dosing consistent with adult dosing recommendations in renal impairment .
See Cefuroxime Sodium Injection USP . |
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MAXIMUM PEDIATRIC
DOSE:
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Up to the maximal adult dosage for the indication .
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ELDERLY DOSE:
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Bone and joint infections-Intramuscular or intravenous, 1.5 grams (base) every eight hours .
Gonococcal infections, disseminated or
Pneumonia, uncomplicated or
Skin and soft tissue infections or
Urinary tract infections, uncomplicated-Intramuscular or intravenous, 750 mg (base) every eight hours .
Gonorrhea, uncomplicated-Intramuscular, 1.5 grams (base) as a single dose at two different sites, in combination with 1 gram of oral probenecid .
Meningitis, bacterial-Intravenous, up to 3 grams (base) every eight hours .
Perioperative prophylaxis-Open heart surgery patients: Intravenous, 1.5 grams (base) at the induction of anesthesia, then 1.5 grams every twelve hours, for a total of 6 grams .
Other surgery patients: Intravenous, 1.5 grams (base) one-half to one hour prior to the start of surgery, then 750 mg (intramuscularly or intravenously) every eight hours thereafter .
For all other infections-Severe or complicated: Intramuscular or intravenous, 1.5 grams (base) every eight hours .
Life-threatening: Intramuscular or intravenous, 1.5 grams (base) every six hours .
Note: Adults with renal function impairment may require a reduction in dose .
See Cefuroxime Sodium Injection USP . |
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