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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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D
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INDICATIONS:
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Anxiety disorder, generalized |
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Panic disorder |
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SIDE EFFECTS:
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emotional lability |
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fatigue |
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flushing |
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galactorrhea |
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gynecomastia |
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hepatic failure |
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hepatitis |
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hyperprolactinemia |
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hypersalivation |
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hyperventilation |
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hypoesthesia |
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hypotension |
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impaired cognition |
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irritability |
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libido decrease |
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libido increase |
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menstrual irregularity |
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physiological dependence |
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psychological dependence |
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Stevens-Johnson syndrome |
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teratogenesis |
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tolerance |
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tremor |
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weight gain |
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weight loss |
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withdrawal |
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xerostomia |
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agitation |
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akathisia |
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amnesia |
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anorexia |
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appetite stimulation |
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ataxia |
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confusion |
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constipation |
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depression |
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dizziness |
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drowsiness |
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dysuria |
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elevated hepatic enzymes |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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anxiety |
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benzodiazepine dependence |
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bipolar disorder |
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children |
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chronic obstructive pulmonary disease (COPD) |
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CNS depression |
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coma |
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dementia |
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depression |
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driving or operating machinery |
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elderly |
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hepatic disease |
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infants |
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labor |
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mania |
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myasthenia gravis |
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neonates |
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obesity |
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Parkinson's disease |
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porphyria |
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pregnancy |
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psychosis |
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pulmonary disease |
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renal failure |
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renal impairment |
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respiratory depression |
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seizure disorder |
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seizures |
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shock |
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sleep apnea |
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status epilepticus |
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substance abuse |
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ADULT DOSE:
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Antianxiety agent-Oral, initially 250 to 500 mcg (0.25 to 0.5 mg) three times a day, the dosage being titrated to the needs of the patient up to a maximum total dose of 4 mg per day .
Note: Debilitated patients-Oral, initially 250 mcg (0.25 mg) two or three times a day, the dosage being increased as needed and tolerated .
The starting dosage may be decreased if adverse effects occur .
Antipanic agent-Oral, initially 500 mcg (0.5 mg) three times a day, the dosage being increased as needed and tolerated up to a maximum of 10 mg per day . |
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MAXIMUM ADULT DOSE:
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PEDIATRIC DOSE:
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Antianxiety or antipanic agent-Children younger than 18 years of age: Safety and efficacy have not been established . |
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MAXIMUM PEDIATRIC
DOSE:
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ELDERLY DOSE:
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Antianxiety agent-Oral, initially 250 mcg (0.25 mg) two or three times a day, the dosage being increased as needed and tolerated . |
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