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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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C
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INDICATIONS:
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Asthma |
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Bronchitis, chronic |
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Emphysema |
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SIDE EFFECTS:
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abdominal pain |
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agitation |
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anorexia |
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anxiety |
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atrial fibrillation |
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atrial flutter |
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atrial tachycardia |
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cardiac arrest |
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diuresis |
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dizziness |
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headache |
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hematemesis |
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hypokalemia |
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hypotension |
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insomnia |
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metabolic acidosis |
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nausea/vomiting |
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palpitations |
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premature ventricular contractions (PVCs) |
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restlessness |
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seizures |
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sinus tachycardia |
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supraventricular tachycardia (SVT) |
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urticaria |
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ventricular tachycardia |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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acidemia |
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breast-feeding |
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cardiac arrhythmias |
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cardiac disease |
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cholestasis |
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cor pulmonale |
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corn hypersensitivity |
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coronary artery disease |
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cystic fibrosis |
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elderly |
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fever |
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gastritis |
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gastroesophageal reflux disease (GERD) |
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heart failure |
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hepatic disease |
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hepatitis |
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hiatal hernia |
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hyperthyroidism |
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hypothyroidism |
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hypoxemia |
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infants |
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myocardial infarction |
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neonates |
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peptic ulcer disease |
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pregnancy |
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prostatic hypertrophy |
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pulmonary edema |
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respiratory infection |
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seizure disorder |
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sepsis |
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shock |
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ADULT DOSE:
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Bronchodilator-Oral, the equivalent of anhydrous theophylline, initially, 300 mg per day. If tolerated, the dosage may be increased after three days, to 400 mg per day. After three more days, the dosage may be increased, if tolerated, to 600 mg per day without measurement of serum concentration. One-half the daily theophylline dose may be given at twelve hour intervals. However, certain patients metabolize theophylline more rapidly, especially the young and those that smoke, and may require dosing at eight hour intervals.
Note: If the 600-mg-per-day dose is to be maintained or exceeded, monitoring of serum theophylline concentration and patient response is recommended to achieve the optimal therapeutic theophylline dosage and minimize the risk of toxicity. |
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MAXIMUM ADULT DOSE:
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PEDIATRIC DOSE:
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Bronchodilator-Children 1 year of age and older, weighing less than 45 kg: Oral, the equivalent of anhydrous theophylline, 12 to 14 mg per kg of body weight, up to a maximum of 300 mg, per day in divided doses. The dosage may be increased, if tolerated, after three days to 16 mg per kg of body weight, up to a maximum of 400 mg, per day. After three more days, if tolerated, the dosage may be increased to 20 mg per kg of body weight up to a maximum of 600 mg, per day. One-half of the daily theophylline dose may be given at twelve-hour intervals. However, younger patients may require dosing at eight-hour intervals.
Children weighing more than 45 kg: See Usual adult dose.
Children 6 to 16 years of age: See Usual adult dose . |
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MAXIMUM PEDIATRIC
DOSE:
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ELDERLY DOSE:
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