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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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B
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INDICATIONS:
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SIDE EFFECTS:
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Headache, continuing |
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hypersensitivity reaction |
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photosensitivity |
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serum sickness-like syndrome |
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Blood dyscrasias, including agranulocytosis or neutropenia |
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aplastic anemia |
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Heinz body or hemolytic anemia |
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leukopenia |
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thrombocytopenia |
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cyanosis |
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exacerbation of ulcerative colitis |
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hepatitis |
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interstitial pneumonitis |
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Stevens-Johnson syndrome |
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systemic lupus erythematosus (SLE)-like syndrome |
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toxic epidermal necrolysis |
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Gastrointestinal disturbances |
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Orange-yellow discoloration of urine or skin |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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>> Allergy, severe |
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>> Asthma, bronchial |
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>> Blood dyscrasias |
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>> Glucose-6-phosphate dehydrogenase deficiency |
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>> Hepatic function impairment |
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>> Porphyria |
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>> Renal function impairment |
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ADULT DOSE:
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Bowel disease (inflammatory) suppressant -
Initial: Oral, 1 gram every six to eight hours. An initial dose of 500 mg every six to twelve hours may be recommended to lessen gastrointestinal side effects.
Maintenance: Oral, 500 mg every six hours, adjusted according to patient response and tolerance.
Antirheumatic (disease-modifying)-
Oral, 500 mg to 1 gram daily for the first week, with the daily dose being increased by 500 mg each week, up to a maintenance dose of 2 grams daily. The dose may be administered two times a day. If no response is seen after two months, the dose may be increased to 3 grams daily. |
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MAXIMUM ADULT DOSE:
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Total daily doses of greater than 4 grams may increase the risk of side effects and toxicity.
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PEDIATRIC DOSE:
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Bowel disease (inflammatory) suppressant -
Infants and children up to 2 years of age-
Use is contraindicated because sulfonamides may cause kernicterus.
Children 2 years of age and older -
Initial-Oral, 6.7 to 10 mg per kg of body weight every four hours; 10 to 15 mg per kg of body weight every six hours; or 13.3 to 20 mg per kg of body weight every eight hours.
Maintenance-Oral, 7.5 mg per kg of body weight every six hours.
Antirheumatic (disease-modifying)-
Safety and efficacy have not been established. |
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MAXIMUM PEDIATRIC
DOSE:
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ELDERLY DOSE:
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Bowel disease (inflammatory) suppressant -
Initial: Oral, 1 gram every six to eight hours. An initial dose of 500 mg every six to twelve hours may be recommended to lessen gastrointestinal side effects.
Maintenance: Oral, 500 mg every six hours, adjusted according to patient response and tolerance.
Antirheumatic (disease-modifying)-
Oral, 500 mg to 1 gram daily for the first week, with the daily dose being increased by 500 mg each week, up to a maintenance dose of 2 grams daily. The dose may be administered two times a day. If no response is seen after two months, the dose may be increased to 3 grams daily. |
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