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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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C
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INDICATIONS:
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SIDE EFFECTS:
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Dyspnea |
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edema |
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flu-like symptoms |
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hyperkinesia |
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hypokinesia |
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mood or mental changes, including abnormal thinking |
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agitation |
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anxiety |
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apathy |
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confusion |
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skin rash |
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Agranulocytosis or neutropenia |
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facial edema |
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impotence |
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menstrual changes |
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mood or mental changes, including delusions |
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depersonalization |
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emotional lability |
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hallucinations |
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hostility |
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mania |
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seizures |
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Constipation |
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dizziness |
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drowsiness |
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dryness of mouth |
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increased appetite |
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weight gain |
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Abdominal pain |
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abnormal dreams |
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asthenia |
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back pain |
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hyperesthesia |
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hypotension |
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increased thirst |
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myalgia |
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nausea |
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orthostatic hypotension |
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tremor |
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urinary frequency |
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vertigo |
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vomiting |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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Cardiovascularr disease that could be exacerbated by hypotension, such as history of myocardial infarction, angina, |
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Conditions that would predispose patients to hypotension, such as dehydration or hypovolemia |
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Drug abuse or dependence |
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>> Hepatic function impairment |
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Mania or hypomania |
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Renal function impairment |
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11 to 39 mL per minute per 1.73 square meters of body surface area ], and by about 50% in patients with severe renal function impairment [GFR < 10 mL/min/1.73m ] ) |
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Seizures |
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ADULT DOSE:
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Antidepressant-
Oral, initially 15 mg once a day, preferably in the evening prior to sleep .
The dose may be increased, as needed and tolerated, at intervals of not less than one to two weeks . |
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MAXIMUM ADULT DOSE:
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Up to 45 mg a day .
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PEDIATRIC DOSE:
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Safety and efficacy have not been established .
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MAXIMUM PEDIATRIC
DOSE:
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ELDERLY DOSE:
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Antidepressant-
Oral, initially 15 mg once a day, preferably in the evening prior to sleep .
The dose may be increased, as needed and tolerated, at intervals of not less than one to two weeks . |
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