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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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C
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INDICATIONS:
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Hypercholesterolemia |
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Hyperlipoproteinemia |
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Pruritus, secondary to biliary obstruction |
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SIDE EFFECTS:
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Constipation |
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Gallstones or pancreatitis |
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gastrointestinal bleeding or peptic ulcer |
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steatorrhea or malabsorption syndrome |
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Heartburn or indigestion |
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nausea or vomiting |
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stomach pain |
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Belching |
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bloating |
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diarrhea |
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dizziness |
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headache |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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Bleeding disorders |
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Gallstones |
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Gastrointestinal function impairment |
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Hypothyroidism |
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Malabsorption states, especially steatorrhea |
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Peptic ulcer |
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>> Complete biliary obstruction or complete atresia |
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>> Constipation |
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Coronary artery disease and |
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Hemorrhoids |
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>> Phenylketonuria |
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Renal function impairment |
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ADULT DOSE:
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Antihyperlipidemic; or
Antipruritic (cholestasis); or
[Antidiarrheal, postoperative colonic bile acids]-Initial: Oral, 4 grams (anhydrous cholestyramine) one or two times a day before meals, adjusted according to response.
Maintenance: Oral, 8 to 24 grams (anhydrous cholestyramine) a day, in two to six divided doses.
Note: A single daily dose or two divided daily doses are equally effective, but up to six divided daily doses may be administered and may be more convenient for the patient, especially with the larger doses. |
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MAXIMUM ADULT DOSE:
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Antihyperlipidemic-24 grams (anhydrous cholestyramine) a day.
Antipruritic (cholestasis)-Up to 16 grams (anhydrous cholestyramine) a day. |
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PEDIATRIC DOSE:
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Antihyperlipidemic-Initial: Oral, 4 grams (anhydrous cholestyramine) a day, in two divided doses.
Maintenance: Oral, 8 to 24 grams (anhydrous cholestyramine) a day, in two or more divided doses. |
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MAXIMUM PEDIATRIC
DOSE:
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ELDERLY DOSE:
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