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PRIMPERAN TABLETS

 

 
 

 

GENERIC NAMES

MANUFACTURERS 

MEDICAL GROUP

MEDICAL ARTICLES

 

DRUGS IN :

 

 

FDA DRUGS

UNITED STATES

CANADA

UNITED KINGDOM

AUSTRALIA

GERMANY

FRANCE

MIDDLE EAST

KUWAIT

LEBANON

EGYPT

SYRIA

BAHRAIN

IRAN

JORDAN

SAUDI ARABIA

UNITED ARAB EMIRATES

 

 

 
 

SIZE:

 

GENERIC NAME:

METOCLOPRAMIDE

 

MANUFACTURER:

SANOFI SYNTHELABO

 

UNIT:

 

ADMINISTRATION ROUTE:

 

FDA PREGNANCY GROUP:

B

 

INDICATIONS:

Gastroesophageal Reflux Disease

Gastroparesis, diabetic

Intubation, intestinal

Nausea, postoperative

Nausea, secondary to cancer chemotherapy

Vomiting, postoperative

Vomiting, secondary to cancer chemotherapy

 

SIDE EFFECTS:

Agranulocytosis

cardiovascular effects, specifically hypotension

hypertension

tachycardia

extrapyramidal effects, dystonic

extrapyramidal effects, parkinsonian

tardive dyskinesia

Agitation

panic-like sensation

restless legs syndrome

Diarrhea

drowsiness

restlessness

unusual tiredness or weakness

Breast tenderness and swelling

changes in menstruation

constipation

dizziness

headache

insomnia

mental depression

prolactin stimulation

nausea

skin rash

unusual dryness of mouth

unusual irritability

 

ABSOLUTE CONTRAINDICATIONS :

 

RELATIVE CONTRAINDICATIONS :

Asthma

Depression, mental

Hypertension

Parkinson's disease

>> Renal failure, severe, chronic

 

ADULT DOSE:

Treatment of diabetic gastroparesis - Oral, 10 mg (base) thirty minutes before symptoms are likely to occur or before each meal and at bedtime, up to four times a day. Note: In the initial treatment of diabetic gastroparesis, the parenteral route of administration is recommended if severe symptoms are present. Therapy may begin at 10 mg (base) administered intramuscularly or intravenously three or four times a day, the dose adjusted as needed. Treatment of gastroesophageal reflux - Oral, 10 to 15 mg (base) thirty minutes before symptoms are likely to occur or before each meal and at bedtime, up to four times a day. Note: Intermittent symptoms may be treated by taking 20 mg of metoclopramide prior to the provoking situation. [Treatment of hiccups] - Oral, 10 to 20 mg (base) four times a day for seven days. An initial dose of 10 mg intramuscularly may be given if necessary. Note: In patients with renal function impairment whose creatinine clearance is less than 40 mL per minute, initial dosage should be reduced by approximately one half .

 

MAXIMUM ADULT DOSE:

500 mcg (0.5 mg) per kg of body weight per day.

 

PEDIATRIC DOSE:

Gastrointestinal emptying (delayed) adjunct or Peristaltic stimulant- Oral, 0.1 to 0.2 mg per kg of body weight per dose, given thirty minutes before meals and at bedtime. 

 

MAXIMUM PEDIATRIC DOSE:

 

ELDERLY DOSE:

 

 

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