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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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B
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INDICATIONS:
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Gastroesophageal Reflux Disease |
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Gastroparesis, diabetic |
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Intubation, intestinal |
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Nausea, postoperative |
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Nausea, secondary to cancer chemotherapy |
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Vomiting, postoperative |
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Vomiting, secondary to cancer chemotherapy |
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SIDE EFFECTS:
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Agranulocytosis |
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cardiovascular effects, specifically hypotension |
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hypertension |
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tachycardia |
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extrapyramidal effects, dystonic |
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extrapyramidal effects, parkinsonian |
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tardive dyskinesia |
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Agitation |
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panic-like sensation |
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restless legs syndrome |
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Diarrhea |
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drowsiness |
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restlessness |
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unusual tiredness or weakness |
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Breast tenderness and swelling |
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changes in menstruation |
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constipation |
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dizziness |
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headache |
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insomnia |
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mental depression |
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prolactin stimulation |
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nausea |
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skin rash |
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unusual dryness of mouth |
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unusual irritability |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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Asthma |
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Depression, mental |
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Hypertension |
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Parkinson's disease |
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>> Renal failure, severe, chronic |
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ADULT DOSE:
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Gastrointestinal emptying (delayed) adjunct or
Peristaltic stimulant-
Intravenous, 10 mg as a single dose.
[Treatment of hiccups] -
Intramuscular, 10 mg initially, followed by oral metoclopramide at a dose of 10 to 20 mg four times a day for seven days.
Antiemetic: For prevention of cancer chemotherapy-induced emesis-
Intravenous infusion, 2 mg per kg of body weight, administered thirty minutes before cisplatin or other highly emetogenic chemotherapeutic agent; may be repeated as needed every two or three hours.
Note: For prevention of emesis induced by chemotherapeutic agents with low emetic potential-Intravenous infusion, 1 mg per kg of body weight.
Continuous intravenous infusion, 3 mg per kg of body weight before chemotherapy, followed by 0.5 mg per kg of body weight per hour for eight hours.
Antiemetic: For prevention of postoperative emesis-
Intramuscular, 10 to 20 mg near the end of surgery. |
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MAXIMUM ADULT DOSE:
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PEDIATRIC DOSE:
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Antiemetic-For prevention of cancer chemotherapy-induced emesis or
Gastrointestinal emptying (delayed) adjunct or
Peristaltic stimulant-
Intravenous, 1 mg per kg of body weight as a single dose. May be repeated one time after sixty minutes.
Note: To reduce the chance of increased adverse reactions, dosages should not exceed 2 mg per kg of body weight. Some clinicians recommend concurrent therapy with diphenhydramine at an intravenous dose of 1 mg per kg of body weight 15 minutes prior to metoclopramide infusion to limit side effects that may occur with doses of less than 2 mg per kg of body weight. |
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MAXIMUM PEDIATRIC
DOSE:
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ELDERLY DOSE:
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