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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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B
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INDICATIONS:
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Acromegaly |
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Adenoma, prolactin- secreting |
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Hyperprolactinemia |
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Parkinson's disease |
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SIDE EFFECTS:
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Confusion |
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dyskinesia |
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hallucinations |
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Myocardial infarction |
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seizures or strokes |
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Cerebrospinal fluid rhinorrhea |
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fainting |
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gastrointestinal hemorrhage or peptic ulcer |
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retroperitoneal fibrosis |
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Hypotension, especially orthostatic hypotension |
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nausea |
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Constipation |
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diarrhea |
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drowsiness or tiredness |
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dry mouth |
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leg cramps at night |
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loss of appetite |
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mental depression |
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Raynaud's phenomenon |
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stomach pain |
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stuffy nose |
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vomiting |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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Hepatic function impairment |
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Hypertension, |
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Hypertension, pregnancy-induced |
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Psychiatric disorders |
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ADULT DOSE:
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Amenorrhea, secondary, due to hyperprolactinemia or
Galactorrhea due to hyperprolactinemia or
Hypogonadism, male, due to hyperprolactinemia or
Infertility due to hyperprolactinemia-Initial: Oral, 1.25 to 2.5 mg at bedtime with a snack. Dosage may be increased by 2.5 mg every three to seven days as needed to a total of 5 to 7.5 mg a day taken in divided doses with meals .
Maintenance: Oral, 2.5 mg two or three times a day with meals. Doses of up to 15 mg have been used .
Prolactinomas, pituitary-Initial: Oral, 1.25 mg two or three times a day with meals. Dosage adjustment is gradual over several weeks to 10 to 20 mg a day taken in divided doses with meals .
Occasionally, higher doses may be required .
Maintenance: Oral, 2.5 to 20 mg a day taken in divided doses with meals .
Parkinsonism-Initial: Oral, 1.25 mg one or two times a day with meals; for single doses, at bedtime with a snack is preferred. Dosage may be increased by 2.5 mg increments every fourteen to twenty-eight days .
Maintenance: Oral, 2.5 to 40 mg a day, taken in divided doses with meals. Although higher doses have been used, safety and efficacy have not been established with doses greater than 100 mg a day .
Acromegaly-Initial: Oral, 1.25 to 2.5 mg at bedtime with a snack for 3 days; dosage may be increased by 1.25 or 2.5 mg every three to seven days up to 30 mg a day taken in divided doses with meals or at bedtime with a snack .
Maintenance: Oral, 10 to 30 mg a day taken in divided doses with meals or at bedtime with a snack. Up to 100 mg per day has been used .
[Lactation suppression] -Initial: Oral, 2.5 mg twice a day taken with meals. Patient may begin medication only after vital signs stabilize and no sooner than four hours after delivery .
Maintenance: Oral, 2.5 to 7.5 mg a day taken in divided doses with meals or at bedtime with a snack for fourteen days. Has been used for up to twenty-one days if needed .
[Neuroleptic malignant syndrome] -Initial: Oral, 5 mg once a day taken at bedtime with a snack; dosage adjustment titrated according to patient response by 2.5 mg increments a day as needed, taken in divided doses with meals or at bedtime with a snack .
Maintenance: Oral, up to 20 mg a day taken in divided doses with meals or at bedtime with a snack . |
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MAXIMUM ADULT DOSE:
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PEDIATRIC DOSE:
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Children up to 15 years of age: Dosage has not been established .
Children 15 years of age and older: See Usual adult dose .
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MAXIMUM PEDIATRIC
DOSE:
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ELDERLY DOSE:
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