OXYTETRACYCLINE CAPSULES

Brucellosis- Oral, 500 mg (base) every six hours for three weeks, given concurrently with 1 gram of streptomycin intramuscularly every twelve hours for the first week and once a day for the second week . Gonorrhea, uncomplicated- Oral, 1.5 grams (base) initially, then 500 mg every six hours for a total dose of 9 grams . Syphilis- Oral, 500 mg to 1 gram (base) every six hours for ten to fifteen days for a total dose of 30 to 40 grams . For all other infections- Oral, 250 to 500 mg (base) every six hours .

MAXIMUM ADULT DOSE:

4 grams (base) daily.

PEDIATRIC DOSE:

For all infections- Children older than 8 years of age: Oral, 6.25 to 12.5 mg (base) per kg of body weight every six hours . Note: Infants and children 8 years of age and younger-All tetracyclines form a stable calcium complex in any bone-forming tissue. As a result, tetracyclines may cause permanent yellow-gray-brown staining of the teeth, as well as enamel hypoplasia. Also, a decrease in linear skeletal growth rate may occur in premature infants. Therefore, use of tetracyclines is not recommended in patients in these age groups unless other medications are unlikely to be effective or are contraindicated.

MAXIMUM PEDIATRIC DOSE:

ELDERLY DOSE:

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