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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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X
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INDICATIONS:
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Infertility |
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Ovulation, induction |
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SIDE EFFECTS:
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Severe ovarian hyperstimulation syndrome |
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Erythrocytosis |
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Gynecomastia |
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Uncomplicated, mild to moderate, ovarian enlargement or ovarian cysts |
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pain, swelling, or irritation at injection site |
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rash at injection site or on body |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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ADULT DOSE:
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Induction of ovulation-
Intramuscular, 75 Units of FSH and 75 Units of LH activity once a day for usually seven or more days, followed by 5000 to 10,000 Units of chorionic gonadotropin one day after the last dose of menotropins .
If necessary, the dose of menotropins may be increased by 75 to 150 Units FSH and 75 to 150 Units LH every four or five days .
Up to 450 Units FSH and 450 Units LH a day may be required.
Assisted reproductive technologies -
Intramuscular, 150 Units of FSH and 150 Units of LH activity once a day for usually seven or more days, followed by 5000 to 10,000 Units of chorionic gonadotropin one day after the last dose of menotropins .
If necessary, the dose of menotropins may be increased by 75 to 150 Units FSH and 75 to 150 Units LH every four or five days.
Note: Dosage regimen may vary according to physician preference or patient response.
If the ovaries are abnormally enlarged or the serum estradiol concentration is excessively elevated on the last day of menotropins therapy, human chorionic gonadotropin should not be given for that cycle.
Male infertility (hypogonadotropic hypogonadism)-
Intramuscular, 75 Units of FSH and 75 Units of LH activity three times a week (plus chorionic gonadotropin 2000 Units twice a week) for at least four months following pretreatment with chorionic gonadotropin (5000 Units three times a week for up to four to six months) .
If an increase in spermatogenesis has not occurred after four months, the dose may be increased to 150 Units FSH and 150 Units LH three times a week (with no change in dose of chorionic gonadotropin) . |
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MAXIMUM ADULT DOSE:
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PEDIATRIC DOSE:
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MAXIMUM PEDIATRIC
DOSE:
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ELDERLY DOSE:
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