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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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C
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INDICATIONS:
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Edema |
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Edema, pulmonary |
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Hypertension, essential |
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SIDE EFFECTS:
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hypovolemia |
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interstitial nephritis |
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jaundice |
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leukopenia |
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nausea/vomiting |
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orthostatic hypotension |
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pancreatitis |
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paresthesias |
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photosensitivity |
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polyuria |
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thrombocytopenia |
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tinnitus |
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abdominal pain |
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acute generalized exanthematous pustulosis (AGEP) |
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agranulocytosis |
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anemia |
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anorexia |
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aplastic anemia |
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azotemia |
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blurred vision |
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cholestasis |
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constipation |
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diarrhea |
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dizziness |
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headache |
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hearing loss |
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hypercholesterolemia |
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hyperglycemia |
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hypertriglyceridemia |
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hyperuricemia |
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hypocalcemia |
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hypochloremia |
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hypokalemia |
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hypomagnesemia |
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hyponatremia |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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acute myocardial infarction |
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breast-feeding |
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diabetes mellitus |
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diarrhea |
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eclampsia |
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elderly |
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gout |
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hearing impairment |
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heart failure |
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hepatic disease |
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hyperglycemia |
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hyperuricemia |
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hypocalcemia |
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hypochloremia |
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hypokalemia |
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hypomagnesemia |
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hyponatremia |
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neonatal prematurity |
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pancreatitis |
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preeclampsia |
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pregnancy |
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renal disease |
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renal failure |
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renal impairment |
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sulfonamide hypersensitivity |
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systemic lupus erythematosus (SLE) |
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thiazide diuretic hypersensitivity |
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ADULT DOSE:
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Diuretic-Oral, initially 20 to 80 mg as a single dose, the dosage then being increased by an additional 20 to 40 mg at six- to eight-hour intervals, until the desired response is obtained. The maintenance dose as determined by titration is then given daily as a single dose or divided into two or three doses, given once a day every other day, or given once a day for two to four consecutive days out of each week.
Antihypertensive-Oral, initially 40 mg two times a day, the dosage then being adjusted according to patient response.
[Antihypercalcemic] -Oral, 120 mg a day as a single dose or divided into two or three doses.
Note: Geriatric patients may be more sensitive to the effects of the usual adult dose. |
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MAXIMUM ADULT DOSE:
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600 mg a day.
Note: In chronic renal failure, doses of up to 4 grams a day have been used.
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PEDIATRIC DOSE:
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Diuretic-Oral, initially 2 mg per kg of body weight as a single dose, the dosage then being increased by an additional 1 to 2 mg per kg of body weight at six- to eight-hour intervals, until the desired response is obtained.
Note: Doses as large as 5 mg per kg of body weight may be required in some children with nephrotic syndrome.
Doses greater than 6 mg per kg of body weight are not recommended.
Dosing interval should be extended in neonates because of prolonged half-life. |
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MAXIMUM PEDIATRIC
DOSE:
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ELDERLY DOSE:
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