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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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C
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INDICATIONS:
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Malaria |
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Malaria, prophylaxis |
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SIDE EFFECTS:
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Abnormal dreams |
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asthenia |
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forgetfulness |
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hypertension |
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hypotension |
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insomnia |
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Arrhythmia |
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cardiopulmonary arrest |
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central nervous system (CNS) disturbances or neuropsychiatric toxicity |
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convulsions |
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encephalopathy |
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erythema multiforme and/or Stevens-Johnson syndrome |
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leukopenia |
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thrombocytopenia |
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Abdominal pain |
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arthralgia and/or myalgia |
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diarrhea |
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dizziness |
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fever |
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headache |
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nausea |
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vomiting |
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Anorexia |
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Alopecia |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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>> Epilepsy |
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>> Seizure disorder |
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>> Heart block, first or second degree |
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>> Psychiatric disorders |
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ADULT DOSE:
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Malaria (prophylaxis)-
Oral, 250 mg once a week, starting one to two weeks before travel, then weekly during travel in malarious areas and for four weeks after leaving those areas .
Malaria (treatment)-
Oral, 1250 mg as a single dose, or 16.5 mg per kg of body weight as a single dose .
Alternatively, 750 mg followed by 500 mg 8 hours later may be considered . |
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MAXIMUM ADULT DOSE:
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PEDIATRIC DOSE:
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Malaria (prophylaxis)-
Infants and children up to 15 kg of body weight: Oral, 5 mg .
Children 15 to 19 kg of body weight-Oral, 62.5 mg (1/4 tablet) once a week, starting one to two weeks before travel, then weekly during travel in malarious areas and for four weeks after leaving endemic areas .
Children 20 to 30 kg of body weight-Oral, 125 mg (1/2 tablet) once a week, starting one to two weeks before travel, then weekly during travel in malarious areas and for four weeks after leaving endemic areas .
Children 31 to 45 kg of body weight-Oral, 187.5 mg (3/4 tablet) once a week, starting one to two weeks before travel, then weekly during travel in malarious areas and for four weeks after leaving endemic areas .
Children over 45 kg of body weight-See Usual adult and adolescent dose .
Malaria (treatment)-
See Usual adult and adolescent dose . |
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MAXIMUM PEDIATRIC
DOSE:
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ELDERLY DOSE:
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