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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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C
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INDICATIONS:
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SIDE EFFECTS:
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Hypoglycemia-mild, including nocturnal hypoglycemia |
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weight gain |
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Erythema multiforme or exfoliative dermatitis |
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hypoglycemia-severe |
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Dilutional hyponatremia, hypo-osmolality, or syndrome of inappropriate antidiuretic hormone (SIADH) |
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Anemia, aplastic or hemolytic |
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blood dyscrasias, specifically, agranulocytosis, leukopenia, pancytopenia |
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cholestasis, cholestatic jaundice, hepatic function impairment, hepatic porphyria, hepatitis, or porphyria cutanea tarda |
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eosinophilia |
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thrombocytopenia |
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Changes in sense of taste |
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dizziness |
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drowsiness |
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gastrointestinal disturbances |
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headache |
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polyuria |
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Blurred vision and/or changes in accommodation |
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photosensitivity |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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Allergy to sulfonylurea antidiabetic agents, sulfonamides, or thiazide-type diuretics |
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>> Diarrhea, severe |
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>> Gastroparesis |
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>> Intestinal obstruction |
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>> Vomiting, prolonged |
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>> Other conditions causing delayed food absorption |
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>> Hepatic disease |
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>> Hyperglycemia-causing conditions |
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Female hormone changes |
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Fever, high |
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Hyperadrenalism, not optimally controlled |
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Infection, severe |
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Psychological stress |
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>> Hyperthyroidism, not optimally controlled |
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>> Hypoglycemia-causing conditions |
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Adrenal insufficiency, not optimally controlled |
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Debilitated physical condition |
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Malnutrition |
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Pituitary insufficiency, not optimally controlled |
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Hypothyroidism, not optimally controlled |
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>> Renal function impairment |
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ADULT DOSE:
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Antidiabetic-Initial: Oral, 160 mg two times a day with meals.
Maintenance: Oral, 80 to 320 mg a day with meals. |
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MAXIMUM ADULT DOSE:
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320 mg daily.
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PEDIATRIC DOSE:
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Safety and efficacy have not been established.
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MAXIMUM PEDIATRIC
DOSE:
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ELDERLY DOSE:
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Antidiabetic-Initial: Oral, 160 mg two times a day with meals.
Maintenance: Oral, 80 to 320 mg a day with meals. |
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