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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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B
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INDICATIONS:
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Ankylosing spondylitis |
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Arthritis, osteoarthritis |
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Arthritis, rheumatoid |
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Dysmenorrhea |
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Inflammation, opthalamic, postoperative |
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Keratosis, actinic |
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Pain, mild to moderate |
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Pain, ophthalmic |
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Photophobia, postoperative |
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SIDE EFFECTS:
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aplastic anemia |
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aseptic meningitis |
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azotemia |
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blurred vision |
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confusion |
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conjunctivitis |
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constipation |
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corneal edema |
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corneal erosion |
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diarrhea |
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dizziness |
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dyspepsia |
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dysphagia |
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elevated hepatic enzymes |
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erythema multiforme |
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esophageal stricture |
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esophageal ulceration |
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esophagitis |
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fluid retention |
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gastritis |
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GI bleeding |
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GI perforation |
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headache |
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heart failure |
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hematuria |
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hemolytic anemia |
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hepatic necrosis |
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hepatitis |
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infection |
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interstitial nephritis |
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iritis |
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jaundice |
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keratitis |
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melena |
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nausea/vomiting |
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nephrotic syndrome |
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ocular irritation |
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ocular pain |
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odynophagia |
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pancreatitis |
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pancytopenia |
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peptic ulcer |
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peripheral edema |
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photophobia |
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platelet dysfunction |
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porphyria |
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proteinuria |
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pruritus |
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purpura |
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pyrosis (heartburn) |
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renal failure (unspecified) |
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renal papillary necrosis |
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Stevens-Johnson syndrome |
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tinnitus |
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urticaria |
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visual impairment |
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xerophthalmia |
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abdominal pain |
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acute generalized exanthematous pustulosis (AGEP) |
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agranulocytosis |
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anaphylactoid reactions |
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anemia |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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acute bronchospasm |
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alcoholism |
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anemia |
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anticoagulant therapy |
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asthma |
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benzyl alcohol hypersensitivity |
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breast-feeding |
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chemotherapy |
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children |
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coagulopathy |
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contact lenses |
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corticosteroid therapy |
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dehydration |
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dental disease |
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dental work |
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diabetes mellitus |
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edema |
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elderly |
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exfoliative dermatitis |
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GI bleeding |
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GI disease |
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heart failure |
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hemophilia |
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hepatic disease |
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hypertension |
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hypovolemia |
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immunosuppression |
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jaundice |
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labor |
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nasal polyps |
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neutropenia |
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ocular exposure |
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ocular surgery |
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peptic ulcer disease |
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porphyria |
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pregnancy |
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renal disease |
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renal failure |
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renal impairment |
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rheumatoid arthritis |
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skin abrasion |
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sunlight (UV) exposure |
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surgery |
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systemic lupus erythematosus (SLE) |
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thrombocytopenia |
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tobacco smoking |
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ulcerative colitis |
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ADULT DOSE:
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Analgesic and
Antidysmenorrheal-Oral, 50 mg three times a day as needed. If necessary, 100 mg may be administered for the first dose only.
Rheumatoid arthritis-Oral, 150 to 200 mg per day in three or four divided doses, initially. After a satisfactory response has been obtained, dosage should be reduced to the minimum dose that provides continuing control of symptoms, usually 75 to 100 mg a day in three divided doses.
Osteoarthritis- Oral, 100 to 150 mg per day in two or three divided doses, initially. After a satisfactory response has been obtained, dosage should be reduced to the minimum dose that provides continuing control of symptoms.
Ankylosing spondylitis - Oral, 100 to 125 mg a day in four or five divided doses, initially. After a satisfactory response has been obtained, dosage should be reduced to the minimum dose that provides continuing control of symptoms. |
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MAXIMUM ADULT DOSE:
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Analgesic and
Antidysmenorrheal-Up to 200 mg on the first day, then 150 mg per day thereafter.
Rheumatoid arthritis- 225 mg per day.
Osteoarthritis- 150 mg per day; higher doses have not been studied. |
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PEDIATRIC DOSE:
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Safety and efficacy have not been established.
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MAXIMUM PEDIATRIC
DOSE:
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ELDERLY DOSE:
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