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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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C
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INDICATIONS:
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SIDE EFFECTS:
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abdominal pain |
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agranulocytosis |
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anemia |
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angioedema |
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aplastic anemia |
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arthralgia |
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blurred vision |
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cholestasis |
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diarrhea |
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dyspepsia |
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erythema |
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hemolysis |
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hypoglycemia |
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hyponatremia |
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jaundice |
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leukopenia |
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maculopapular rash |
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nausea/vomiting |
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pancytopenia |
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photosensitivity |
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pruritus |
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pyrosis (heartburn) |
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secondary failure |
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SIADH |
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thrombocytopenia |
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urticaria |
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vasculitis |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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breast-feeding |
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children |
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coma |
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elderly |
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hepatic disease |
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infection |
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obstetric delivery |
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pregnancy |
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renal disease |
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renal impairment |
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surgery |
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thyroid disease |
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ADULT DOSE:
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Antidiabetic-Initial: Oral, 2.5 to 5 mg once a day with breakfast or the first main meal, with dosage changes being made by no more than 2.5 mg at weekly intervals if needed. Patients more sensitive to hypoglycemia may need 1.25 mg a day.
Maintenance: Oral, 1.25 to 20 mg a day, of which doses up to 10 mg are usually taken as a single dose with breakfast or the first main meal, while doses over 10 mg are usually divided into two daily doses with meals. |
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MAXIMUM ADULT DOSE:
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20 mg daily.
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PEDIATRIC DOSE:
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Safety and efficacy have not been established.
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MAXIMUM PEDIATRIC
DOSE:
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ELDERLY DOSE:
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Antidiabetic-Initial: Oral, 1.25 to 2.5 mg a day with breakfast, with dosage changes being made by no more than 2.5 mg at weekly intervals if needed.
Maintenance: See Usual adult dose .
Note: This dose should also be used in patients with medical problems that make them more sensitive to the effects of glyburide. |
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