DANOL CAPSULES

Endometriosis-Moderate to severe: Oral, 400 mg two times a day (beginning Day 1 of menstruation, if possible) for at least three to six months, and may be continued for nine months if necessary. Mild: Oral, 100 to 200 mg two times a day (beginning Day 1 of menstruation, if possible) for at least three to six months, and may be continued for nine months if necessary. Note: If symptoms recur after discontinuation of therapy, therapy may be reinstituted. Fibrocystic breast disease-Oral, 50 to 200 mg two times a day (beginning Day 1 of menstruation, if possible) for six months or until the symptoms completely disappear, whichever comes first. Note: If symptoms recur within one year of discontinuation of therapy, therapy may be reinstituted. Hereditary angioedema, prophylaxis of -Oral, initially 200 mg two or three times a day until the desired initial response is obtained; then the maintenance dosage is determined by decreasing the initial dosage by 50% or less at intervals of one to three months or longer, depending on the frequency of attacks prior to treatment. Note: Daily dosage may be increased by up to 200 mg if the condition is not controlled at lower doses. [Primary menorrhagia]-Oral, 200 to 400 mg a day, in divided doses (beginning Day 1 of menstruation, if possible), for up to six months. Note: If no improvement is seen after two or three cycles, therapy should be discontinued and the cause of the excess bleeding reassessed.

MAXIMUM ADULT DOSE:

800 mg per day.

PEDIATRIC DOSE:

Dosage has not been established.

MAXIMUM PEDIATRIC DOSE:

ELDERLY DOSE:

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