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SIZE:
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GENERIC NAME:
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MANUFACTURER:
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UNIT:
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ADMINISTRATION ROUTE:
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FDA PREGNANCY GROUP:
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B
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INDICATIONS:
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Vaginosis, bacterial |
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Abscess, intra- abdominal |
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Abscess, pulmonary |
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Abscess, tubo- ovarian |
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Acne vulgaris |
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Cellulitis, pelvic |
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Empyema |
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Endometritis |
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Infection, bone |
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Infection, gynecologic |
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Infection, intra- abdominal |
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Infection, joint |
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Infection, lower respiratory tract |
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Infection, skin and skin structure |
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Infection, vaginal cuff |
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Peritonitis |
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Pneumonia |
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Pneumonitis, anaerobic |
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Septicemia |
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SIDE EFFECTS:
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Pseudomembranous colitis |
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Hypersensitivity |
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neutropenia |
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thrombocytopenia |
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Gastrointestinal disturbances |
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Fungal overgrowth |
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Severe abdominal or stomach cramps and pain |
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abdominal tenderness |
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watery and severe diarrhea, which may also be bloody |
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fever |
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ABSOLUTE
CONTRAINDICATIONS :
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RELATIVE
CONTRAINDICATIONS : |
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>> Gastrointestinal disease, history of, especially ulcerative colitis, regional enteritis, or antibiotic-associated colitis |
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>> Hepatic function impairment, severe |
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Hypersensitivity to lincomycins or doxorubicin |
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Renal function impairment, severe |
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ADULT DOSE:
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Antibacterial-Intramuscular or intravenous, 300 to 600 mg (base) every six to eight hours; or 900 mg every eight hours.
[Babesiosis (treatment)] -Intravenous, 300 to 600 mg clindamycin (base) four times a day with concurrent oral administration of 650 mg of quinine, three or four times a day for seven to ten days.
[Pneumonia, Pneumocystis carinii (treatment)] -Intravenous, 2400 to 2700 mg (base) per day in divided doses in combination with 15 to 30 mg of primaquine daily.
[Toxoplasmosis, central nervous system (CNS) (treatment)] -Intravenous, 1200 to 4800 mg (base) per day in divided doses in combination with 50 to 100 mg of pyrimethamine daily. |
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MAXIMUM ADULT DOSE:
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Up to 2.7 grams (base) daily.
Note: Doses up to 4.8 grams daily have been used. However, some medical experts recommend a maximum dose of 2.7 grams daily.
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PEDIATRIC DOSE:
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Antibacterial-Infants up to 1 month of age: Intramuscular or intravenous, 3.75 to 5 mg (base) per kg of body weight every six hours; or 5 to 6.7 mg per kg of body weight every eight hours.
Infants 1 month of age and over: Intramuscular or intravenous, 3.75 to 10 mg (base) per kg of body weight or 87.5 to 112.5 mg per square meter of body surface every six hours; or 5 to 13.3 mg per kg of body weight or 116.7 to 150 mg per square meter of body surface every eight hours.
Note: In children, regardless of body weight, the minimum recommended dose is 300 mg (base) daily for severe infections.
Bone infection-Intramuscular or intravenous, 7.5 mg per kg of body weight every six hours.
[Babesiosis (treatment)] -Dosage has not been established; however, based on one case report in an infant, the suggested dose is: Intravenous or intramuscular, 20 mg per kg of body weight per day of clindamycin with concurrent oral administration of 25 mg per kg of body weight per day of quinine for seven to ten days. |
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MAXIMUM PEDIATRIC
DOSE:
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ELDERLY DOSE:
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