BACTRIM SYRUP

Antibacterial (systemic)- Oral, 800 mg of sulfamethoxazole and 160 mg of trimethoprim every twelve hours. Antiprotozoal- Pneumocystis carinii pneumonia - Treatment: Oral, 18.75 to 25 mg of sulfamethoxazole and 3.75 to 5 mg of trimethoprim per kg of body weight every six hours for fourteen to twenty-one days . Prophylaxis : Oral, 800 mg of sulfamethoxazole and 160 mg of trimethoprim once a day. Acceptable alternative dosing schedules include- Oral, 800 mg of sulfamethoxazole and 160 mg of trimethoprim three times a week (e.g., Monday, Wednesday, Friday) . Oral, 400 mg of sulfamethoxazole and 80 mg of trimethoprim once a day . [Toxoplasmosis (prophylaxis)] - Oral, 800 mg of sulfamethoxazole and 160 mg of trimethoprim once a day. Acceptable alternative dosing schedules include: Oral, 800 mg of sulfamethoxazole and 160 mg of trimethoprim three times a week (e.g., Monday, Wednesday, Friday) . Oral, 400 mg of sulfamethoxazole and 80 mg of trimethoprim once a day. [ HIV-related infection in Africa (prophylaxis)] - Oral, 800 mg of sulfamethoxazole and 160 mg of trimethoprim once a day .

MAXIMUM ADULT DOSE:

PEDIATRIC DOSE:

Antibacterial (systemic)- Infants up to 2 months of age- Use is not recommended since sulfonamides may cause kernicterus in neonates. Infants 2 months of age and over- Infants and children up to 40 kg of body weight-Oral, 20 to 30 mg of sulfamethoxazole and 4 to 6 mg of trimethoprim per kg of body weight every twelve hours. Children 40 kg of body weight and over-See Usual adult and adolescent dose. Antiprotozoal- Pneumocystis carinii pneumonia (PCP)- Treatment: Oral, 18.75 to 25 mg of sulfamethoxazole and 3.75 to 5 mg of trimethoprim per kg of body weight every six hours for fourteen to twenty-one days. Prophylaxis : Children 4 weeks of age and over- Oral, 375 mg of sulfamethoxazole per square meter and 75 mg of trimethoprim per square meter of body surface two times a day, three times a week on consecutive days (e.g., Monday, Tuesday, Wednesday). Acceptable alternative dosing schedules include - Oral, 750 mg of sulfamethoxazole per square meter and 150 mg of trimethoprim per square meter of body surface as a single daily dose three times a week on consecutive days (e.g., Monday, Tuesday, Wednesday). Oral, 375 mg of sulfamethoxazole per square meter and 75 mg of trimethoprim per square meter of body surface two times a day seven days a week. Oral, 375 mg of sulfamethoxazole per square meter and 75 mg of trimethoprim per square meter of body surface two times a day, three times a week on alternate days (e.g., Monday, Wednesday, Friday). Note: PCP prophylaxis is recommended for all infants born to HIV-infected mothers starting at 4 weeks of age, regardless of their CD4 lymphocyte counts. However, if the infant is receiving zidovudine during the first 6 weeks of life for the prevention of perinatal HIV transmission, sulfamethoxazole and trimethoprim combination prophylaxis should be delayed until zidovudine is discontinued at 6 weeks of age, to reduce the chance of anemia that may occur if these two medications are given concurrently. [Toxoplasmosis (prophylaxis)] - Oral, 375 mg of sulfamethoxazole per square meter and 75 mg of trimethoprim per square meter of body surface two times a day, three times a week on consecutive days (e.g., Monday, Tuesday, Wednesday). Acceptable alternative dosing schedules include: Oral, 750 mg of sulfamethoxazole per square meter and 150 mg of trimethoprim per square meter of body surface as a single daily dose three times a week on consecutive days (e.g., Monday, Tuesday, Wednesday). Oral, 375 mg of sulfamethoxazole per square meter and 75 mg of trimethoprim per square meter of body surface two times a day seven days a week. Oral, 375 mg of sulfamethoxazole per square meter and 75 mg of trimethoprim per square meter of body surface two times a day, three times a week on alternate days (e.g., Monday, Wednesday, Friday). [HIV-related infection in Africa (prophylaxis)] - Studies have not been performed in children .

MAXIMUM PEDIATRIC DOSE:

ELDERLY DOSE:

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